4 Myths About the Abortion Pill Mifepristone, Debunked

A recent lightning rod for abortion opponents, the drug mifepristone—the first of two in the standard medication abortion regimen—surfaced several times during Robert F. Kennedy, Jr.’s first Senate confirmation hearing as President Trump’s pick for Health and Human Services secretary. The question of whether Kennedy, if confirmed, will seek to curb access to it or at least raise the scrutiny around it looms large, given recent (unsuccessful) legal efforts by anti-abortion advocates to reverse its FDA approval. (To be clear, that would have a catastrophic impact on abortion access writ large, as medication accounts for more than 60% of US abortions, according to 2023 data from the Guttmacher Institute.)
In questioning Kennedy, both Montana Rep. Senator Steve Daines and Oklahoma Rep. Senator James Lankford brought up often-cited concerns among anti-abortion advocates about the safety of mifepristone and criticized its widespread accessibility. Kennedy’s response was simply that he’d implement whatever policies around the drug Trump decides are best, noting that the President “hasn’t taken a stand on how to regulate it” yet and has asked him to “study the safety” of the drug in order to do so.
But make no mistake: Mifepristone has been thoroughly studied over several decades and the results of that research clearly demonstrate its safety and efficacy for folks who want to end a pregnancy in the first trimester. Read on to learn more about the claims that suggest otherwise—and why you shouldn’t believe these myths.
First, let’s break down how we ended up here.
The FDA approved mifepristone for medication abortion in September 2000, but people who were prescribed the drug could only get it by going to an authorized clinic, medical office, or hospital, thanks to an “in-person dispensing requirement.” (Remember this part—it will come up a lot.) The FDA first eased some of its restrictions on the drug in 2016, which included expanding the gestational age limit to end a pregnancy from seven weeks to 10.
In April 2021, the FDA officially stopped enforcing the in-person dispensing requirement while COVID-19 remained a public health emergency—meaning, people who were prescribed mifepristone could use mail-order pharmacies to get it, a major win because a lot of reproductive health clinics had temporarily shuttered, leaving people who needed abortion care with few options. Removing the in-person dispensing requirement became official later that year, with the caveat that pharmacies needed to be certified to offer the medication.
Then Roe v. Wade, the landmark case that guaranteed the right to an abortion, was overturned in June 2022. Several states have since imposed tight restrictions on abortion care access, some have banned it completely, and others have become safe havens (including via telemedicine) for people who need this form of health care.
Though Conservative judges and lawmakers have claimed that Roe’s reversal would just “send abortion back to the states,” a case challenging access to mifepristone reached the Supreme Court in March 2024. (The lawsuit was filed by a group of anti-abortion doctors who relied on retracted research for the basis of it; they claimed that the FDA failed to account for all the potential dangers of the drug when approving and expanding access to it.) Ultimately, the court dismissed the case, citing a lack of legal standing—in other words, the plaintiffs weren’t experiencing any real harm from the FDA’s actions, so they couldn’t sue. But just this month, a Texas federal judge ruled that three states (Missouri, Idaho, and Kansas) can pick the lawsuit back up in a lower court. (Loosened FDA regulations on the drug, they claim, undermine their state laws that heavily restrict abortion access.)

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